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Dendreon Takes Huge Hit, Stock Tanks 60% on Sales Shortfall

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a patient’s PSA score, and then had to endure lots of uncertainty about whether they’d get reimbursed for an expensive medicine, Gold said. And while Dendreon has insisted that the $93,000 price is in line with other cancer drugs, many of the other products reach that price over months or years, not a single expensive month, like Provenge does. The phenomenon, in which so much of the cost is at the front end of the treatment process, makes Provenge a product with high “cost density” which has made physicians wary, Gold said.

This is a big deal for Dendreon, because it will need to win over community physicians in a much bigger way, and go far beyond a few rarefied academic centers, if it wants to reach the multi-billion dollar sales potential that many analysts have predicted. Gold insisted that the market size hasn’t changed, just that it will take longer to grow than the company predicted.

“We see this as a shift of the growth curve to the right,” Gold said.

Dendreon didn’t say how deep its cost-cutting will have to go, or how many people it will need to axe from the payroll to counteract the slow product launch. The company said in its most recent quarterly report that it had about 1,915 employees as of June 30.

Analysts will surely start penciling out how deep the cuts will need to go in order to preserve Dendreon’s existing cash position. The company had about $674 million in cash and investments on hand at the end of June, and burned through about $106 million of its cash reserves in the most recent quarter ended June 30, according to Greg Schiffman, the company’s finance chief. Assuming a cash burn rate of about $30 million a month, if nothing changes, the company has about six quarters worth of cash on its books to run the business, he said.

The cuts will come during this quarter, to provide clarity as soon as possible for investors and employees, Schiffman said.

Dendreon, in its summary of the quarter, pointed the blame mostly at itself. The company needs to educate physicians about how the reimbursement process has been streamlined, it needs to do more to help doctors identify the patients who are candidates for the product, and it needs to “streamline the customer experience” to make it easier for doctors and patients, Gold said.

David Miller, an analyst with Biotech Stock Research in Seattle, summed up the situation in a line. “Docs are not prescribing Provenge until they are certain they are going to be reimbursed.”

And analysts on the call made it clear they aren’t going to be making bullish sales projections anymore, at least until they start seeing real evidence that more doctors around the U.S. are prescribing the new treatment with confidence that they will get paid.

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  • Steve Bozeman

    Mitchell Gold should be fired. DNDN should have pre-announced this miss. It sure didn’t stop him from being nothing but enthusiastic 45 days ago at the annual shareholders meeting. This miss is almost criminal. I do not trust management and Wall st will not trust them again. You can count on that.

    Thanks for you coverage Luke. I feel terrible for the people in Seattle that will lose their jobs.

  • Jake Moore

    Mitchell Gold should be one of the employees “layed off” (FIRED!). He has made well over $50 million over the last 3 years and can afford to be out of a job. He deserves to be let go more than ANY OTHER employee. Yet, being at the top, I seriously doubt that would ever cross his mind to terminate himself. BUT, that is WHAT SHOULD HAPPEN, yet we all know, that would NEVER HAPPEN. They have known for many months of this problem, and if they did not,that is even more evidence of incompetence of management. Gold must go!

    Jake from Birmingham, Alabama

  • John Smith

    Gold’s share sales say it all. He needs to be investigated.

  • Ben

    What a scam. The shareholders and employees of Dendreon who will lose their jobs are left holding the bag while Mitchell Gold and his cronies return to their mansions.

    Gold makes a rather large sale right before the earnings debacle…sounds a little suspicious. Hope the SEC checks this out.

  • Steve—thanks for the comment. It’s kind of amazing to me how the Provenge manufacturing constraints were such a focus for so long, while reimbursement was essentially pooh-poohed on the Street as a non-issue, at least since the Medicare advisory panel recommended Provenge reimbursement in November. It makes me wonder if lingering skittishness among doctors about reimbursement is the core of the issue, or whether there’s something else equally worrisome holding this product back.

    Whatever it really is, there’s no doubt this is very bad news for folks who work at Dendreon, for its investors, and for the Seattle biotech community.

  • FL Williams

    Luke, Where was the Board of Directors in this mess? Where was the Chairman of the Board? Why didn’t the Board insist upon pre-notification to the key funds that had several hundreds of millions at risk with Dendreon. What were they thinking? That this was a game? Luke it isn’t just Dendreon that has a problem. It is all of those that put hard earned capital at risk and did not receive the proper notification 6 weeks ago that sales weren’t up to snuff. Luke, there is something very fishy here. Afterall, several officers at Dendreon had sales of shares since June. Yes, some would argue they were planned. But, with proper notification, those sales could have been cancelled. This is a very serious breach of management, Luke and needs to be treated as such.

  • Ronald D

    Who is their VP of Sales and Marketing? He isn’t listed on the management section of their website. But they have a VP of HR listed. Interesting.

  • Rajesh

    DNDN is done. Their high priced vaccine will kill them for good. They want to gobble the money within a month and be done.

    The next vaccine revolution will come from ADXS (Advaxis). The science is revolutionary and ultra safe, efficacy is probably the best out there by a long margin exhibited even during phase I trials. Just go to their website, educate yourself with their investor presentation file and other details. They will leave DNDN in the dust in another 3 years.

    You heard it here first!!!

  • Gold & the Board of Directors should be fired. The company should be investigated. They sold a lot of stock 2 weeks leading up to the earnings announcement. They should reimburse the company for the stock they sold as their results are atrociously bad. They left the shareholders holding a bag of empty nuggets. They should have pre-announced instead of shocking investors. Sounds like a huge scam to me.

  • R. Jones

    The outpouring of concern that we are not getting this valuable treatment to enough prostate cancer patients is touching.


    As an oncology practice administrator other than the high cost another issue is the data itself- patients may be hesitant to use a drug with 4 month survival when there are other options available. And if medicare remibursement decreases to ASP + 4 next year,
    these very expensive drugs could be difficult to justify administering in the community setting

  • Kathy Cabiness

    I am disappointed in myself that I am shocked by people’s concentration on only the financial side effects of this mismanagement!
    Get with it, folks. So there is an incompetent greedy person at the top..spread
    the word from the grass roots about the easy, cheap availability of the drug.

  • al00z


  • Lonnie Olsen

    Bottom line more than 1/3 of all prostate cancers are Indolent and require no treatment at all. The patient will most likely die from other causes. Doctors are not going to jump on board and start prescribing this treatment when it is not required. Good treatment option yes. In most cases no. Blockbuster No

  • Garth

    Mitch Gold has been fired. Soon to follow will be Rob Rosen and all the rest of the scum. Justice has been served.

  • Garth


    Cheap????? What are you smoking? The drug is $93,000 per treatment in addition in a study that Dendreon buried (which is now leading to medicare fraud)indicated that only people with certain Genetic markers show progress with Provenge. That’s 60% of the population. Provenge is a joke.