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What We Learned in San Diego About Innovation: Five Lessons for Detroit


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emerging science-based technologies are crucial factors in shaping the economic winners and losers of the first half of the 21st century. To create international comparative advantage in a knowledge-based economy, clustering innovative activity is imperative.”

—Collaborate. “Not-invented here” is not an acceptable culture. Institutions need to work with industry, industry needs to work with local government, and local government must be educated by all of the above. Sharing knowledge and experience in the startup phase helps everyone learn faster and provides a comparative advantage. There is plenty of opportunity to compete in the marketplace.

—Establish non-profit organizations like San Diego’s CONNECT. CONNECT was created by regional leaders in research, government and the private sector to support local entrepreneurship and technology innovation. We help connect entrepreneurs with the investors, lawyers, financial firms, and others they need to start high technology and life sciences companies. We help provide professional mentoring, and host events that are intended to educate and provide forums for discussion, and an impetus for working together.

[Editor’s note: To help launch Xconomy Detroit, we’ve queried our network of Xconomists and other innovation leaders around the country for their list of the most important things that entrepreneurs and innovators in Michigan can do to reinvigorate their regional economy.]

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Duane J. Roth was Chief Executive Officer and board member of CONNECT, the San Diego nonprofit organization that fosters entrepreneurship by catalyzing, accelerating, and supporting technology and life sciences innovation. He founded Alliance Pharmaceutical, and was a longtime life sciences industry executive. Follow @

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  • JB

    “San Diego added 1,100 new technology-related jobs. And the salaries in those jobs are nearly twice the average wages in the area. I recommend a recent column on “Just Doing It” by Thomas Friedman in the New York Times.”

    An item to note; San Diego is extremely cost prohibitive for an average family. The higher wages in San Diego may actually still provide a lower standard of living than an average salary in Detriot.

    I’d be careful of copying anything in CA, anything, if I were a government official. Texas is a better study, imho, Austin in particular.

  • jwilly48519

    Statistically, “high tech” companies are most frequently started by professors, grad students and recent advanced-degree graduates in engineering, the sciences and management…and most frequently in the “light” sciences, i.e. EE, bio, information tech, where commercialization of ideas is relatively less capital intensive.

    Michigan has relatively few of these kinds of individuals, especially in the ex-industrial cities. Michigan’s universities and intellectual talent pool overall tend to be more focused on mechanical engineering and on turning out individuals with BS degrees, who go on to be someone else’s employee. Nothing wrong with that, but it doesn’t get new high tech businesses started.

    Offering such entrepreneurs what the ex-industrial cities have in abundance… empty buildings; lots of underutilized, previous-generation support infrastructure; available talent for mechanical-product manufacturing… is ineffective.

    The most important factor in location-selection for high-tech entrepreneurs is where they want to live. They typically want excellent schools, low crime, a generally intelligence-valuing society, social life populated mostly by professionals like themselves. The ex-industrial cities have trouble competing on that basis.

    All of the above are readily discerned by study of the high tech nexuses since WWII, starting with the 128/495 belt around Boston/Cambridge.

    The only historically proven way to attract high tech entrepreneurs to a locale that doesn’t meet the above criteria is by throwing money at them…selectively, one hopes. But, that has obvious problems.