Why Are Drugs Getting Such Weird Brand Names?

5/9/11Follow @ldtimmerman

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to a scientific audience that it was a hybrid compound with two ways of working, and that it looked and sounded like “vitality.” The part that made it sound like a hybrid is important to physicians who are used to seeing depression drugs that are pretty much all alike, while the “vitality” part sounds good to a patient who wants help with depression.

If you are Seattle Genetics, and selling a new drug for Hodgkin’s disease and other rare, deadly lymphoma, you don’t really need to appeal to the consumer masses. That’s partly why the company settled on “Adcetris” for its new drug. The thinking was that for physician/scientists, starting the name with the letters ADC would call to mind the drug’s scientific origins as an antibody drug conjugate. That’s a jargon term that Seattle Genetics has used for years to describe its technique of linking, or “conjugating” an antibody to a toxin that makes the drug more potent.

I’ve written about antibody drug conjugates for years, and personally didn’t get the ADC connection at first glance. And I joked with Bruce Seeley, Seattle Genetics’ executive vice president of commercial operations, that I accidentally typed “Adcentris” a couple times before I could get the spelling right. It didn’t seem to bug him—he said the team at Seattle Genetics is happy that the FDA agreed to allow “Adcetris” to stand.

“I’ve named quite a few products in my history, and it’s increasingly difficult to find an attractive name that doesn’t sound like something else, or have a patient safety issue associated with it,” Seeley says. “We’re very fortunate.”

I thought it would be fun to comb through a list of recent names of drugs that have been FDA approved, or newly coined by the manufacturers, to give you a chance to weigh in on which ones you like, and which ones you don’t. There are 18 new drugs listed in the chart below. Below the chart, you can vote on the best and worst names in the bunch. Of course, you’re also welcome to leave your comments at the bottom of this story, too. This is an entirely unscientific poll, but it seems like fun. Who knows, if this exercise uncovers some fun new facts or insights, I might even share the results in a future BioBeat column. That is, so long as all these drug names haven’t already put you to sleep.

Scientific name Brand Name Disease Company
telaprevir Incivek Hepatitis C Vertex Pharmaceuticals
boceprevir Victrelis Hepatitis C Merck
brentuximab vedotin Adcetris Hodgkin’s disease Seattle Genetics
abiraterone Zytiga Prostate cancer Johnson & Johnson
cabazitaxel Jevtana Prostate cancer Sanofi-Aventis
belimumab Benlysta Lupus Human Genome Sciences
denosumab Prolia Osteoporosis Amgen
denosumab Xgeva Cancer-related bone fractures Amgen
sipuleucel-T Provenge Prostate Cancer Dendreon
gabapentin enacarbil Horizant Restless Legs Syndrome Xenoport
gabapentin Gralise Postherpetic neuralgia Depomed
peginterferon alfa-2b Sylatron Melanoma Merck
ipilimumab Yervoy Metastatic melanoma Bristol-Myers Squibb
ibuprofen and famotidine Duexis Osteoarthritis, rheumatoid arthritis Horizon Pharma
tocilizumab Actemra Rheumatoid arthritis Roche
roflumilast Daliresp Chronic Obstructive Pulmonary Disease Forest Laboratories
vilazodone Viibryd Depression Clinical Data
azilsartan medoxomil Edarbi Hypertension Takeda Pharmaceuticals

Create your free online surveys with SurveyMonkey, the world’s leading questionnaire tool.

Create your free online surveys with SurveyMonkey, the world’s leading questionnaire tool.

Luke Timmerman is the National Biotech Editor of Xconomy. E-mail him at ltimmerman@xconomy.com Follow @ldtimmerman

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  • David Goldfarb

    Amen, brother. As a pharma marketer, it seems to me the objective is to occupy a space in the mind of the prescriber on the way to “top of mind in the category.” Being uniquely odd just isn’t aiming high enough. One suspects that professional namers are simply keyboarding parameters into a program, letting it run and editing out the candidates with no vowels at all. Does this work? Sure. But naming could be done so much better.

  • http://www.xconomy.com/author/ltimmerman/ Luke Timmerman

    Drum roll please….the votes are in on the best and worst drug names. Here are the top 10 worst names, as selected by you the readers by 6 pm Eastern/3 pm Pacific time.

    Worst:
    Xgeva….27
    Yervoy…20
    Edarbi…16
    Viibryd..10
    Incivek…8
    Zytiga….5
    Duexis….5
    Daliresp..5
    Actemra…4
    Victrelis.4
    Jevtana…3
    Adcetris..2
    Provenge..2
    Horizant..2
    Gralise….2
    Sylatron..2

    I’ll add another comment for the names you voted in as the best.

  • http://www.xconomy.com/author/ltimmerman/ Luke Timmerman

    Here are the votes for the best drug names:

    Best:
    Provenge…39
    Benlysta…27
    Prolia…..21
    Incivek….10
    Horizant….9
    Victrelis…8
    Viibryd…..7
    Adcetris….5
    Yervoy……4
    Actemra…..4

    The polls are now closed. SurveyMonkey wants me to pay for more results, and since this was just for fun, I’m not going to. I’m not sure what to conclude here, other than we have a lot of Dendreon fans stuffing the ballot box, like many probably will for Ichiro at this year’s All-Star game. Thanks for sharing your thoughts!

  • Ellen M Martin

    Viibryd sounds like a new humanoid species in a science fiction universe…

  • http://www,natrapharm.com Chito Aquino

    i also voted for Provenge as the one i like most because its an action name..the revenge of of the prostate to ward off cancer cells.easier for the doctors to recall and “feel good” for patients.I dont like Galise because in the Philippines Galis is a stubborn wound.It should avoid this connotation if it wants to gain a good international brand image.Overall thank you for the mental exercise.

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  • LJ

    It is Gralise, not Galise. And it is now Depomed’s, not Abbott’s.

  • http://www.xconomy.com/author/ltimmerman/ Luke Timmerman

    LJ—good catch, thanks. After writing this, I also realize I forgot a few drugs that would have been fun to include in the mix. I’m thinking of Arena Pharmaceuticals’ lorcaserin (Lorqess) for obesity, Orexigen Therapeutics’ combination of naltrexone and bupropion (Contrave) for obesity, Amylin Pharmaceuticals exenatide once-weekly (Bydureon) for diabetes, and Optimer Pharmaceuticals’ fidaxomicin (Dificid) for C. difficile infections.

  • http://www.thinkresultsmarketing.com Jenn LeBlanc

    Completely agree. Naming products in the pharma space is so much more cpmplex as there are even more criteria to consider beyond brand image and the basic marketing criteria. All the good ones are taken. Not surprised about the results of the poll. The best names are still easy to pronounce and spell. Even in pharma.

    Nice post. Well done.

  • Leonard Drake

    I am baffled by half of the names of the newer medications being advertised: Yaz, Beyaz, Lyrica, et al. When I think of “Lyrica,” I think of someone or something singing. “Lyrica” has no relation to fibromyalgia, but then again, the name Tylenol doesn’t “scream” headache, either.

    And Yaz? Ever since problems were reported with Yaz we can “BE Yaz?” What the….?

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