Hygeia Therapeutics Aims Synthetic Hormone Therapies At Aging Boomers (Men and Women Alike)

11/29/10Follow @xconomy

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isn’t just restricted to the vaginal region, though, Schwartz says. Skin thins throughout the entire body as it ages, causing bruising and greater fragility, so HYG-102 could be used throughout the entire body and also by men. “We don’t know what the market is for skin fragility, except that every elderly person has it,” Schwartz says. “It’s a normal consequence of aging.”

Therapeutic applications could extend further with the synthetic hormone blocking product, HYG-440, in Hygeia’s pipeline. The topical treatment, also built on technology licensed from Hochberg’s Yale lab, could help target acne, excess facial hair in women, and androgenic baldness, Schwartz says. That product isn’t as far along in development as HYG-102, but she says the firm is expecting some “pivotal proof of concept data” on it next month.

Hygeia was founded in 2007 and raised $1 million in Series A financing this past spring. The firms’ scientific advisory board includes Hochberg, and Elkan Gamzu, also the company chairman who has experience at biotechs such as Millennium Pharmaceuticals, Epix Pharmaceuticals, and Cambridge Neuroscience. Hygeia’s plans to “stay very lean as a nod to the economy,” Schwartz says. She and co-founder Craig Abolin, also a Sepracor alum, comprise Hygeia’s full-time team and focus on drug development. Medical, legal, and financial tasks at the firm are all contracted out.

The startup is exploring options for Series B investors, but has also received interest from bigger drug companies for partnership opportunities, Schwartz says. The dermatological market is promising, because of the greater ease of conducting clinical trials and the easily observed results, she says. “There’s a real need out there for dermatological products.”

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  • http://www.ButifulMe.com Anieta V.

    Another solution for the greedy pharmaceuticals with no second thought given to the overall health (aka wealth) of the person who is to try this.
    Just like HRT, we now come to discover the detrimental effects of too much estrogen leading to cancer.
    Anti-again involves the whole body, not just a small part of your skin. People can easily learn about their hormones and what influences them. Our bodies have numerous hormones and overstimulating one affects the others. Too much estrogen results in bad-estrogen, something every person probably already has because of an overload of plastics and toxins in our system. Everyone should just start with cleansing regularly and eating a healthy diet.

  • Pushga

    Anieta V., your literary ignorance is glaring. If you read, and understood the article, you’d have noticed this company is developing safer alternatives to esttrogen.
    I think this company is on to something terrific. It will be interesting to see how they progress.