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	<title>Comments on: Genzyme Gene Therapy Fails To Help People with Leg Disease Walk Longer</title>
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	<link>http://www.xconomy.com/boston/2009/03/31/genzyme-gene-therapy-fails-to-help-people-with-leg-disease-walk-longer/</link>
	<description>Business + Technology in the Exponential Economy</description>
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		<title>By: Genzyme Gene Therapy Fails To Help People with Leg Disease Walk Longer &#124; Xconomy&#160;&#124;&#160;.gen Technologies Inc.</title>
		<link>http://www.xconomy.com/boston/2009/03/31/genzyme-gene-therapy-fails-to-help-people-with-leg-disease-walk-longer/comment-page-1/#comment-112174</link>
		<dc:creator>Genzyme Gene Therapy Fails To Help People with Leg Disease Walk Longer &#124; Xconomy&#160;&#124;&#160;.gen Technologies Inc.</dc:creator>
		<pubDate>Mon, 01 Mar 2010 20:52:57 +0000</pubDate>
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		<description>[...] http://www.xconomy.com/boston/2009/03/31/genzyme-gene-therapy-fails-to-help-people-with-leg-disease-... [...]</description>
		<content:encoded><![CDATA[<p>[...] <a href="http://www.xconomy.com/boston/2009/03/31/genzyme-gene-therapy-fails-to-help-people-with-leg-disease-.." rel="nofollow">http://www.xconomy.com/boston/2009/03/31/genzyme-gene-therapy-fails-to-help-people-with-leg-disease-..</a>. [...]</p>
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		<title>By: Genzyme in the News: Bayer Deal, Failed Gene Therapy Trial &#124; IguanaBio - A Daily Biotech and Pharma Tabloid - Gossip, News, Humor and Updates on the Latest Events in the Biotechnology and Pharmaceutical Industries</title>
		<link>http://www.xconomy.com/boston/2009/03/31/genzyme-gene-therapy-fails-to-help-people-with-leg-disease-walk-longer/comment-page-1/#comment-52417</link>
		<dc:creator>Genzyme in the News: Bayer Deal, Failed Gene Therapy Trial &#124; IguanaBio - A Daily Biotech and Pharma Tabloid - Gossip, News, Humor and Updates on the Latest Events in the Biotechnology and Pharmaceutical Industries</dc:creator>
		<pubDate>Tue, 31 Mar 2009 21:00:46 +0000</pubDate>
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		<description>[...] Genzyme also made some headlines this weekend on news of a failed gene therapy trial. Xconomy reported that the study looked at 289 patients with peripheral arterial disease (PAD) who were injected with either a placebo, low, medium, or high dose of a HIF-1 alpha gene. The treatment failed to show that it could increase treadmill walking time before disabling pain or fatigue caused patients to stop (intermittent claudication). Patients were examined at six months and followed for two years. The study was presented this past weekend at the American College of Cardiology annual meeting. [Xconomy] [...]</description>
		<content:encoded><![CDATA[<p>[...] Genzyme also made some headlines this weekend on news of a failed gene therapy trial. Xconomy reported that the study looked at 289 patients with peripheral arterial disease (PAD) who were injected with either a placebo, low, medium, or high dose of a HIF-1 alpha gene. The treatment failed to show that it could increase treadmill walking time before disabling pain or fatigue caused patients to stop (intermittent claudication). Patients were examined at six months and followed for two years. The study was presented this past weekend at the American College of Cardiology annual meeting. [Xconomy] [...]</p>
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