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	<title>Comments on: Biogen Idec, Elan Report Two New Cases of Rare Brain Infection in Tysabri Patients</title>
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	<link>http://www.xconomy.com/boston/2008/07/31/biogen-idec-elan-report-two-new-cases-of-rare-brain-infection-in-tysabri-patients/</link>
	<description>Business + Technology in the Exponential Economy</description>
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		<title>By: Trends blog &#187; Blog Archive &#187; tysabri</title>
		<link>http://www.xconomy.com/boston/2008/07/31/biogen-idec-elan-report-two-new-cases-of-rare-brain-infection-in-tysabri-patients/comment-page-1/#comment-27375</link>
		<dc:creator>Trends blog &#187; Blog Archive &#187; tysabri</dc:creator>
		<pubDate>Wed, 03 Sep 2008 05:59:03 +0000</pubDate>
		<guid isPermaLink="false">http://www.xconomy.com/?p=3660#comment-27375</guid>
		<description>[...] Biogen Idec, Elan Report Two New Cases of Rare Brain Infection in &#8230;Cambridge, MA-based Biogen Idec (NASDAQ: BIIB) and Ireland’s Elan reported some serious bad news this afternoon on their multiple sclerosis drug Tysabri. Two new patients taking the drug in Europe have developed the rare and often fatal &#8230; [...]</description>
		<content:encoded><![CDATA[<p>[...] Biogen Idec, Elan Report Two New Cases of Rare Brain Infection in &#8230;Cambridge, MA-based Biogen Idec (NASDAQ: BIIB) and Ireland’s Elan reported some serious bad news this afternoon on their multiple sclerosis drug Tysabri. Two new patients taking the drug in Europe have developed the rare and often fatal &#8230; [...]</p>
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		<title>By: Barbara</title>
		<link>http://www.xconomy.com/boston/2008/07/31/biogen-idec-elan-report-two-new-cases-of-rare-brain-infection-in-tysabri-patients/comment-page-1/#comment-25118</link>
		<dc:creator>Barbara</dc:creator>
		<pubDate>Sun, 03 Aug 2008 23:08:11 +0000</pubDate>
		<guid isPermaLink="false">http://www.xconomy.com/?p=3660#comment-25118</guid>
		<description>It is my understanding that both people where male not sure if the other 2 cases where males also maybe this is a factor just a though.</description>
		<content:encoded><![CDATA[<p>It is my understanding that both people where male not sure if the other 2 cases where males also maybe this is a factor just a though.</p>
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		<title>By: Mark Wendman</title>
		<link>http://www.xconomy.com/boston/2008/07/31/biogen-idec-elan-report-two-new-cases-of-rare-brain-infection-in-tysabri-patients/comment-page-1/#comment-25104</link>
		<dc:creator>Mark Wendman</dc:creator>
		<pubDate>Sun, 03 Aug 2008 16:26:21 +0000</pubDate>
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		<description>I am curious if Tsyabri works by combating the seemingly little known but apparent 100% correlation of MS to a specific viral infection. 

Granted this is little known (hence not yet generally accepted), but Dr. ?Chris Powers up in Alberta (UofA) apparently found a 100% correlation to a human endogenous virus ( I hope I have the nomenclature correct ).  

If this is true, and if this is the as yet not generally accepted but possibly true cause of MS, I am curious if Tsyabri has any impact upon the associated viral load from the specific infection.

My impression is that many of the research efforts into MS treatments have not looked at possible viral causes to MS, and if Dr. Powers&#039; research is correct, then I think  some folks need to start giving serious consideration to anti-viral strategies for treatment and hopefully curing MS, possibly by developing a genetically engineered solution to the gene damage that the specific virus is creating ( in effect a counter virus, that might repair only damaged cells / tissue )

There is a short discussion of this towards the end of my old but short blog post on the genesis of Adherex, a cadherin cell adhesion pharma development firm that is applying cadherin chemistry to beating cancers. 

Recent results of Adherex include in a Phase 1 combo trial for advanced untreatable Melanoma, Adherex had 8 of 16 patients gain complete remission from advanced melanoma,  with no remaining traces of tumors, and of the remaining 8 patients in the P1, 4 had partial remission, and 4 had stable disease. All in a P1 trial intended typically for toxicity testing. So I think Adherex is on to something by using a specific cadherin antagonist to increase the effectiveness of cancer treatments significantly.

Towards the end of this article, is a description of Dr. Powers&#039; correlation of a viral infection to clinical MS.

http://mark-nano.blogspot.com/2006/02/article-on-genesis-of-adherex.html</description>
		<content:encoded><![CDATA[<p>I am curious if Tsyabri works by combating the seemingly little known but apparent 100% correlation of MS to a specific viral infection. </p>
<p>Granted this is little known (hence not yet generally accepted), but Dr. ?Chris Powers up in Alberta (UofA) apparently found a 100% correlation to a human endogenous virus ( I hope I have the nomenclature correct ).  </p>
<p>If this is true, and if this is the as yet not generally accepted but possibly true cause of MS, I am curious if Tsyabri has any impact upon the associated viral load from the specific infection.</p>
<p>My impression is that many of the research efforts into MS treatments have not looked at possible viral causes to MS, and if Dr. Powers&#8217; research is correct, then I think  some folks need to start giving serious consideration to anti-viral strategies for treatment and hopefully curing MS, possibly by developing a genetically engineered solution to the gene damage that the specific virus is creating ( in effect a counter virus, that might repair only damaged cells / tissue )</p>
<p>There is a short discussion of this towards the end of my old but short blog post on the genesis of Adherex, a cadherin cell adhesion pharma development firm that is applying cadherin chemistry to beating cancers. </p>
<p>Recent results of Adherex include in a Phase 1 combo trial for advanced untreatable Melanoma, Adherex had 8 of 16 patients gain complete remission from advanced melanoma,  with no remaining traces of tumors, and of the remaining 8 patients in the P1, 4 had partial remission, and 4 had stable disease. All in a P1 trial intended typically for toxicity testing. So I think Adherex is on to something by using a specific cadherin antagonist to increase the effectiveness of cancer treatments significantly.</p>
<p>Towards the end of this article, is a description of Dr. Powers&#8217; correlation of a viral infection to clinical MS.</p>
<p><a href="http://mark-nano.blogspot.com/2006/02/article-on-genesis-of-adherex.html" rel="nofollow">http://mark-nano.blogspot.com/2006/02/article-on-genesis-of-adherex.html</a></p>
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