Comments on: GlaxoSmithKline Scoops Up Sirtris

By: jerr

jerr — Sat, 30 May 2009 01:20:52 +0000

My bet is that if this stuff really works as good as advertised– it disappears! If things sound too good to be true, if it is true it puts too many people out of business.

By: Gina Mortimer

Gina Mortimer — Wed, 27 May 2009 23:36:08 +0000

How can I participate in the clinical trials?

By: John Gall

John Gall — Sat, 18 Apr 2009 16:37:16 +0000

I have been taking 480 mg 99% Resveratrol combined with 0,350 mg Quercetin (99%) (all together as Q increases biovailability of RV.) very single day since last october 2008.
At the time I started, I stopped all and any intake of B Agonist,steroids and anti cholinergics.(B AGONIST I STOPPED 2 YRS AGO THEY KILL)
My FEV1 was at the time 44%.30 day s after was 48% today is is 53%.
No medication at all.I feel great,I walked yesterday 300 meters in 3′04 and not exhausted (128 ppm).My weight is the same.My muscular mass increased and fats are gone.My liver,great,my lipids,down,choleterol,down.Sexual life:improved a lot.¡ That is fantastic ¡
I must say that Resveratrol comes form ayurvedic medicine 300 years BC.And it should be taked in his natural form from Polygonum Cuspidatum roots and very carefully purified.Must take care from who you buy.I feel very bad at looking the marketing and irresponsible publicity from 99% of anouncements.

By: Donna Ruffini

Donna Ruffini — Wed, 25 Mar 2009 17:05:25 +0000

please come up with an inexpensive natural form of Resveratrol to be sold locally.

Approximately 80% of
Americans are overweight & this seems as though it can assist, however, these people also live below the poverty line & cannot afford to pay $87/month. We need someone to care enough & avoid those imitation products being sold. The public needs the real thing at an inexpensive cost.
thank you

By: Donna Ruffini

Donna Ruffini — Wed, 25 Mar 2009 16:59:02 +0000

How can I become a member of a human trial for resveratrol?

3/25/09

By: Kemos

Kemos — Thu, 05 Feb 2009 01:12:16 +0000

I find it odd that a “resveratrol” search at GSK’s website brings up 0 results.

By: Hugh Hamilton

Hugh Hamilton — Tue, 27 Jan 2009 09:56:57 +0000

How can I become a member of a human trial for resveratrol?

By: Cheryl Zeranti

Cheryl Zeranti — Mon, 26 Jan 2009 13:03:28 +0000

How can I become a member of a human trial for resveratrol?

By: Resveratrol wine

Resveratrol wine — Thu, 30 Oct 2008 21:45:15 +0000

“To succeed Glaxo will have to come up with sythetic versions of resveratrol that are shown to be clearly superior to resveratrol itself and just as safe.”
I think I disagree with that, since latest news tell us even 3-4 glasses of red wine might do the trick as well- provided that you have picked the right wine. What do you believe that Sirtris will do after these news and how will people react? Will they choose the supplements or a glass of red wine?

By: Greg

Greg — Thu, 28 Aug 2008 14:20:24 +0000

The t1/2 of invivo resveratrol in humans is extraordinarily short. It was not detectable in humans after an IV infusion (speaking of native resveratrol and not metabolites). There is much invitro data concerning effective applications of native resv which does not translate to animal models (likely due to inadequate exposure). As such, there is an extraordinary potential in the formulating of analogues of resveratrol. Those herbal pills likely do not have the potentail to exploit the beneficial effects resveratrol offers.

By: Mary Wright

Mary Wright — Wed, 23 Apr 2008 00:14:56 +0000

Natural high potency resveratrol is available now.
Resveratrol can help you to lead a long and healthy life so says Dr. Oz.
Resveratrol Supplements can help you control your weight naturally
by increasing energy, reducing cravings, and limiting your appetite.
According to Wikipedia, Consumer Lab, an independent dietary
supplement and over the counter products evaluation organization,
published a report on 13 November 2007 on the popular resveratrol
supplements. The organization reported that there exists a wide range
in quality, dose, and price among the 13 resveratrol products
evaluated. The actual amount of resveratrol contained in the
different brands range from 2.2mg for Revatrol, which claimed to have
400mg of “Red Wine Grape Complex”, to 500mg for Biotivia.com Transmax,
which is consistent with the amount claimed on the product’s label.
Prices per 100mg of resveratrol ranged from less than $.30 for
products made by Biotivia.com, jarrow, and country life, to a high of
$45.27 for the Revatrol brand. None of the products tested were found
to have significant levels of heavy metals or other contaminants.

By: Dr. James Harding

Dr. James Harding — Tue, 22 Apr 2008 23:36:07 +0000

As I see it the dilemma for Sirtris, and now Glaxo is that the products they are developing already exist in effective natural, inexpensive form. Given, his synthetic analogs may be more potent or targeted against specific conditions such; however biotivia transmax, the natural form of concentrated resveratrol, is available now and has been shown in peer reviewed studies to be safe and effective. Synthetic analogs historically have been shown to be somewhat unpredictable in effect and safety. Why not simply stick with the natural form? It is here now and does not require an expensive physician’s appointment. To succeed Glaxo will have to come up with sythetic versions of resveratrol that are shown to be clearly superior to resveratrol itself and just as safe.