Gerard Karsenty is a Professor and the Chair of the Department of Genetics and Development at the College of Physicians and Surgeons, Columbia University Medical Center, New York. He was educated in France; where he earned a BS in Experimental Science in Beauvais and subsequently was awarded PhD and MD degrees at the Medical School of the University of Paris V in 1984. He spent the following two years as a Visiting Fellow at the National Institutes of Health, first in the Molecular, Cellular and Nutritional Endocrinology Branch of the National Institute of Arthritis, Diabetes, and Digestive and Kidney, and then in the Gene Regulation Section of the Laboratory of Molecular Biology, National Cancer Institute. Following his work at the NIH, Professor Karsenty moved to the University of Texas MD Anderson Cancer Center, Houston, where he worked as a Postdoctoral Fellow and a Research Associate in the Department of Molecular Genetics. He was appointed Assistant Professor in this department in 1990 and Associate Professor in 1996. In 1998, he joined the Baylor College of Medicine in Houston as Associate Professor in the Department of Molecular and Human Genetics; and became Professor in 1999. Professor Karsenty assumed his present position at Columbia University in 2006 and is currently involved in research using mouse genetics to identify novel functional connections between organs and new physiologies relevant to humans. Specifically his lab is studying the skeleton as the organ using the mouse as the model. He is also author of 150 peer-reviewed articles and many invited reviews. Professor Karsenty has been fortunate to receive the following awards: the Drieu-Cholet Award from the French National Academy of Medicine (2006), the Edith and Peter O’Donnell Award from the Academy of Medicine, Engineering and Science of Texas (2006), the Schaefer Award, Columbia University Medical Center (2007), the Lee C. Howley Prize for Arthritis Research presented by the Arthritis Foundation (2008) and the Richard Lounsberry Award from the National Academy of Sciences (USA) and the French Academy of Science (2010). He served as the Associate Editor of the Journal of Bone and Mineral Research from 2003 to 2007 and is the current editor of several scientific journals, including Bone; Journal of Cell Biology; Developmental Cell, Cell Metabolism, Genes and Development and the Journal of Clinical Investigation.