Atul Butte, M.D., Ph.D. is an Assistant Professor in Pediatrics, Medicine (Medical Informatics), and by courtesy, Computer Science, at Stanford University and the Lucile Packard Children's Hospital, and is a pediatric endocrinologist. Dr. Butte received his undergraduate degree in Computer Science from Brown University, and worked in several stints as a software engineer at Apple Computer (on the System 7 team) and Microsoft Corporation (on the Excel team). He graduated from the Brown University School of Medicine, during which he worked as a research fellow at NIDDK through the Howard Hughes/NIH Research Scholars Program. He completed his residency in Pediatrics and Fellowship in Pediatric Endocrinology, both at Children's Hospital, Boston. Dr. Butte received a Ph.D. in Health Sciences and Technology from the Medical Engineering / Medical Physics Program in the Division of Health Sciences and Technology, at Harvard Medical School and Massachusetts Institute of Technology.
Dr. Butte's laboratory focuses on solving problems relevant to genomic medicine by developing new methodologies in translational bioinformatics. The Butte Lab has developed bioinformatics methods to take genomic, genetic, phenotypic, and RNAi data from multiple sources and phenotypes and reason over these data. Example of this method includes work on cancer drug discovery (Proceedings of the National Academy of Science, PNAS, 2000), on type 2 diabetes mellitus (PNAS, 2003), on fat cell formation (Nature Cell Biology, 2005), on obesity (Bioinformatics, 2007), and in transplantation (PNAS, 2009). To facilitate this, the Butte Lab has developed tools to automatically index and find genomic data sets based on the phenotypic and contextual details of each experiment (Nature Biotechnology, 2006), re-mapping microarray data (Nature Methods, 2007), and deconvoluting multi-cellular samples (Nature Methods, 2010). The Butte Lab has also been developing novel methods in conducting basic science using electronic health record systems (Science, 2008), and the first clinical evaluation of a whole human genome (Lancet, 2010).
Dr. Butte has authored more than 80 publications in bioinformatics, medical informatics, and molecular diabetes, and has delivered more than 110 invited presentations world-wide on bioinformatics, including 20 at the National Institutes of Health or NIH-related meetings. Dr. Butte is on the Board of Directors of the American Medical Informatics Association (AMIA), and serves on the Johnson and Johnson Corporate Office of Science and Technology (COSAT). Dr. Butte has co-authored one of the first books on microarray analysis titled "Microarrays for an Integrative Genomics" published by MIT Press. Dr. Butte's research has been featured in the 2008 New York Times Science Times and the International Herald Tribune. Dr. Butte's recent awards include the 2010 Society for Pediatric Research Young Investigator Award, induction into the American College of Medical Informatics in 2009, the 2008 AMIA New Investigator Award, the 2007 Genome Technology "Tomorrow's Principal Investigator" Award, the 2006 Howard Hughes Medical Institute Early Career Award, the 2006 PhRMA Foundation Research Starter Grant in Informatics, and the 2002 and 2003 American Association for Clinical Chemistry Outstanding Speaker Award. Significant research support for Dr. Butte's laboratory comes from grants from eight institutes of NIH and the Howard Hughes Medical Institute.